Molecular characteristics of respiratory syncytial virus (RSV) isolated in the North Vietnam, 2017-2018
نویسندگان
چکیده
Respiratory syncytial virus (RSV) is one of the most interesting respiratory viruses in world. This causes symptoms illnesses like influenza and imposes a heavy burden on medical services economy. However, studies RSV Vietnam are limited, while research has primarily been done before 2015. We collected clinical samples from severe acute infection (SARI) patients to screen for by real-time RT-PCR study their molecular characteristics. RSV-positive specimens with Ct value < 25 between 2017-2018 north were inoculated Hep2 cell line. The results showed that (22.32%) strains harvested inoculation procedure 18 A 7 B. whole genomes four representative sequenced Illumina iSeq 100. Phylogenetic trees analysis each subtype classified as two B sequences genotype ON1 lineage 1.2 BA9 respectively. These genotypes identified typical Vietnamese 2009-2012. Nevertheless, 2015 those this had significant differences G gene, 34–35 amino acids 4 Moreover, first genome since 2016 may give more understanding characteristics RSVs Vietnam.
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ژورنال
عنوان ژورنال: Academia Journal of Biololy
سال: 2022
ISSN: ['2615-9023']
DOI: https://doi.org/10.15625/2615-9023/17209